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Antisoma plc (SRC)

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Thursday 01 July, 2010

Antisoma plc

Holdings in Antisoma






                            Holdings in Antisoma plc

+------------------------------------------------------------------------------+
|TR-1: NOTIFICATION OF MAJOR INTEREST IN SHARES                                |
+----------------------------------------------+-------------------------------+
                                               |
+----------------------------------------------+-------------------------------+
|1. Identity of the issuer or the underlying   |                               |
|issuer                                        |                               |
|of existing shares to which voting rights are |         Antisoma Plc          |
|attached:                                     |                               |
|                                              |                               |
+----------------------------------------------+-------------------------------+
|2. Reason for the notification (please tick the appropriate box or boxes):    |
+----------------------------------------------------------------------+-------+
|An acquisition or disposal of voting rights                           |   X   |
+----------------------------------------------------------------------+-------+
|                                                                      |       |
|An acquisition or disposal of qualifying financial instruments which  |       |
|may result in the acquisition of shares already issued to which voting|       |
|rights are attached.                                                  |       |
|                                                                      |       |
+----------------------------------------------------------------------+-------+
|                                                                      |       |
|An acquisition or disposal of instruments with similar economic effect|       |
|to qualifying financial instruments                                   |       |
|                                                                      |       |
+----------------------------------------------------------------------+-------+
|An event changing the breakdown of voting rights                      |       |
+-----------------------+----------------------------------------------+-------+
|                       |                                              |       |
|Other (please specify):|                                              |       |
|                       |                                              |       |
+-----------------------+--------------+-------------------------------+-------+
|3. Full name of person(s) subject to  |                                       |
|the                                   |            Invesco Limited            |
|notification obligation:              |                                       |
+--------------------------------------+---------------------------------------+
|4. Full name of shareholder(s)        |                                       |
| (if different from 3.):              |                                       |
+--------------------------------------+---------------------------------------+
|                                      |                                       |
|5. Date of the transaction and date on|                                       |
|which the threshold is crossed or     |             28 June 2010              |
|reached:                              |                                       |
|                                      |                                       |
+--------------------------------------+---------------------------------------+
|6. Date on which issuer notified:     |             01 July 2010              |
+--------------------------------------+---------------------------------------+
|7. Threshold(s) that is/are crossed or|                                       |
|reached:                              |                  5%                   |
|                                      |                                       |
+-----------------------+--------------+-------+-----------------------+-------+




+-------------------------------------------------------------------------------+
|8. Notified details:                                                           |
|                                                                               |
+-------------------------------------------------------------------------------+
|A: Voting rights attached to shares                                            |
+------------+----------------------+-------------------------------------------+
|Class/type  |  Situation previous  | Resulting situation after the triggering  |
|of          |  to the triggering   |                transaction                |
|shares      |     transaction      |                                           |
|            +----------+-----------+---------+-----------------+---------------+
|if possible |  Number  |  Number   |         |Number of voting | % of  voting  |
|using       |    of    |    of     | Number  |     rights      |    rights     |
|the ISIN    |  Shares  |  Voting   | f shares+------+----------+------+--------+
|CODE        |          |  Rights   |         |Direct| Indirect |Direct|Indirect|
+------------+----------+-----------+---------+------+----------+------+--------+
|Ordinary 1p |          |           |         |      |          |      |        |
|            |26,130,626|26,130,626 |         |      |31,733,372|      | 5.04%  |
|GB0055696032|          |           |         |      |          |      |        |
+------------+----------+-----------+---------+------+----------+------+--------+

+-------------------------------------------------------------------------------+
|B: Qualifying Financial Instruments                                            |
+-------------------------------------------------------------------------------+
|Resulting situation after the triggering transaction                           |
+--------------+----------+--------------------+------------------+-------------+
|              |          |                    |Number of voting  |             |
|Type of       |Expiration|Exercise/           |rights that may be|% of voting  |
|financial     |date      |Conversion Period   |acquired if the   |rights       |
|instrument    |          |                    |instrument is     |             |
|              |          |                    |exercised/        |             |
|              |          |                    |converted.        |             |
+--------------+----------+--------------------+------------------+-------------+
|              |          |                    |                  |             |
+--------------+----------+--------------------+------------------+-------------+

+-------------------------------------------------------------------------------+
|C: Financial Instruments with similar economic effect to Qualifying Financial  |
|Instruments                                                                    |
+-------------------------------------------------------------------------------+
|Resulting situation after the triggering transaction                           |
+-------------+---------+----------+----------+------------------+--------------+
|             |         |          |          |                  |              |
|Type       of|Exercise |Expiration|Exercise/ |Number  of  voting|%   of  voting|
|financial    |price    |date      |Conversion|rights  instrument|rights        |
|instrument   |         |          |period    |refers to         |              |
|             |         |          |          |                  |              |
+-------------+---------+----------+----------+------------------+-------+------+
|             |         |          |          |                  |Nominal|Delta |
|             |         |          |          |                  +-------+------+
|             |         |          |          |                  |       |      |
+-------------+---------+----------+----------+------------------+-------+------+

+-------------------------------------------------------------------------------+
|Total (A+B+C)                                                                  |
+------------------------------------+------------------------------------------+
|Number of voting rights             |Percentage of voting rights               |
+------------------------------------+------------------------------------------+
|31,733,372                          |5.04%                                     |
+------------+++--------+-+--------+++--------++-----+----------+++----+-+------+




+--------------------------------------------------------------------------+
|9. Chain of controlled undertakings through which the voting rights and/or|
|the                                                                       |
|financial instruments are effectively held, if applicable:                |
+--------------------------------------------------------------------------+
|                                                                          |
| Bank of New York - 31,733,372                                            |
|                                                                          |
|                                                                          |
|                                                                          |
|                                                                          |
|                                                                          |
|                                                                          |
|                                                                          |
|                                                                          |
|                                                                          |
|                                                                          |
|                                                                          |
|                                                                          |
+--------------------------------------------------------------------------+

+--------------------------------------------------------------------------+
|Proxy Voting:                                                             |
+-------------------------------------------------+------------------------+
|10. Name of the proxy holder:                    |                        |
+-------------------------------------------------+------------------------+
|11. Number of voting rights proxy holder will    |                        |
|cease                                            |                        |
|to hold:                                         |                        |
+-------------------------------------------------+------------------------+
|12. Date on which proxy holder will cease to hold|                        |
|voting rights:                                   |                        |
+-------------------------------------------------+------------------------+

+-----------------------------+--------------------------------------------+
|                             |                                            |
|13. Additional information:  |                                            |
+-----------------------------+--------------------------------------------+
|14. Contact name:            |              Samantha Edwards              |
+-----------------------------+--------------------------------------------+
|15. Contact telephone number:|                01491 416381                |
+-----------------------------+-------------------+------------------------+


Enquiries:
Alison Saville, Senior Marketing and Communications Executive
Antisoma plc
+44 (0)20 3249 2100



[HUG#1429029]








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