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Antisoma plc (SRC)

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Monday 23 February, 2009

Antisoma plc

Director Shareholding

Antisoma plc
Company Executive Incentive Plan grant

London, UK, and Cambridge, MA: 23 February 2009
Pursuant to the Antisoma plc Executive Incentive Plan, Antisoma plc
has granted Performance Share awards over ordinary 1p shares to
Directors as follows:

Director            Number of Performance Shares
Glyn Edwards                  693,182
Ursula Ney                    509,091
Eric Dodd                     363,636

Other employees have also been granted Performance Share awards over
a total of 2,225,000 shares.

The above Performance Share grant reflects the Company's practice of
making biannual awards to qualifying employees following release of
the interim and preliminary financial results. The above Directors
and certain employees have agreed to pay the employer's National
Insurance arising on the exercise of their own options.

The Performance Share awards, which are subject to fulfilment of
certain performance and other conditions, have a date of grant of 19
February 2009 and will normally become exercisable for three years,
commencing on 19 February 2012. The Performance Shares are
exercisable at 1p each.

Mr Edwards, Dr Ney and Mr Dodd, as Directors, notified Antisoma plc
of their respective interests in these shares on 19 February 2009.

Alison Saville, Communications Executive              +44 (0)20 3249
Antisoma plc


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