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Antisoma plc (SRC)

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Friday 13 June, 2008

Antisoma plc

Holdings in Antisoma plc





13 June 2008, London, UK:

TR-1:               notification of major
interests in shares


1. Identity of the issuer or the underlying         Antisoma Plc
issuer of existing shares to which voting
rights are attached:

2. Reason for notification (yes/no)
An acquisition or disposal of voting rights
An acquisition or disposal of financial instruments which may
result in the acquisition of shares already issued to which
voting rights are attached
An event changing the breakdown of voting rights               Yes
Other (please specify):______________

3. Full name of person(s) subject to the        Legal & General Group
notification obligation:                              Plc (L&G)
4. Full name of shareholder(s) (if different             n/a
from 3.):
5. Date of the transaction (and date on which       11 June 2008
the threshold is crossed or reached if
different):

6. Date on which issuer notified:                   12 June 2008

7. Threshold(s) that is/are crossed or reached:  From 4% - 3% (L&G)


8. Notified details:



A: Voting rights attached to shares
Class/type Situation previous to the Resulting situation after the triggering
of shares  Triggering transaction    transaction
 if
possible   Number of    Number of    Number of  Number of voting    % of voting
using the  Shares       Voting       shares     rights              rights
ISIN CODE               Rights                  Direct     Indirect Direct Indirect
ORD        18,376,359   18,376,359   19,240,499 19,240,499          3.13
GBP0.01    (Pre         (Pre
           Acquisition) Acquisition)



B: Financial Instruments
Resulting situation after the triggering transaction
Type of    Expiration Exercise/     Number of voting rights    % of
financial  date       Conversion    that may be acquired if    voting
instrument            Period/ Date  the instrument is          rights
                                    exercised/ converted.



Total (A+B)
Number of voting rights % of voting rights
      19,240,499               3.13




9. Chain of controlled undertakings through which the voting rights
and/or the financial instruments are effectively held, if applicable:
Legal & General Group Plc (Direct and Indirect)
(Group)

Legal & General Investment Management (Holdings)
Limited (LGIMH) (Direct and Indirect)

Legal & General Investment Management Limited
(Indirect) (LGIM)

Legal & General Group Plc (Direct) (L&G) (19,240,499 - 3.13% = LGAS,
                             LGPL & PMC)

Legal & General Investment          Legal & General Insurance
Management (Holdings) Limited       Holdings Limited (Direct) (LGIH)
(Direct) (LGIMHD)

Legal & General Assurance (Pensions Legal & General Assurance Society
Management) Limited  (PMC)          Limited  (LGAS & LGPL)
                                    Legal & General Pensions Limited
                                    (Direct)  (LGPL)

Proxy Voting:

10. Name of the proxy holder:                                    N/A

11. Number of voting rights proxy holder will cease to hold:     N/A

12. Date on which proxy holder will cease to hold voting rights: N/A


                                Notification using the total voting
 13. Additional information:       rights figure of  613,528,966

14. Contact name:                       Helen Lewis (LGIM)

15. Contact telephone number:              020 3124 3851



Enquiries: Daniel Elger, Director of Communications, Antisoma plc;
+44(0)20 3249 2100

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