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Lipoxen PLC (XEN)

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Wednesday 21 March, 2007

Lipoxen PLC

Holding(s) in Company

Lipoxen PLC
21 March 2007

                          LIPOXEN PLC (the 'Company')

                NOTIFICATION OF INTEREST IN TOTAL VOTING RIGHTS

A form TR-1 containing the following information has been received by the
Company.

TR-1 notification of major interests in shares

1. Identity of the issuer or the underlying issuer of existing shares to which
voting rights are attached:

LIPOXEN PLC

2. Reason for the notification

Notification for the FSA 20 March 2007 deadline.

3. Full name of person(s) subject to the notification obligation:

Gartmore Investment Limited

4. Full name of shareholder(s) (if different from 3):

GARTMORE SMALLER COMPANIES TRUST PLC 3.617%

5.Date of the transaction (and date on which the threshold

is crossed or reached if different):

N/A

6. Date on which issuer notified:

19 March 2007

7. Threshold(s) that is/are crossed or reached:

Below 5%

8. Notified details:

A: Voting rights attached to shares
Class/type of      Situation previous to the  Resulting situation after the triggering transaction(1)
shares             Triggering transaction
                   Number of     Number of    Number of     Number of voting rights  % of voting rights
 if possible using Shares        Voting       shares
the ISIN CODE                    Rights       Direct        Direct      Indirect     Direct    Indirect
GB00B08NWV55                     7%           8,387,301     nil         8,387,301    nil       7.234%


B: Financial Instruments
Resulting situation after the triggering transaction
Type of financial    Expiration date Exercise/ Conversion      Number of voting rights    % of voting
instrument                           Period/ Date              that may be acquired if    rights
                                                               the instrument is
                                                               exercised/ converted.




Total (A+B)
Number of voting rights                              % of voting rights

8,387,301                                            7.234%



9. Chain of controlled undertakings through which the voting rights and/or the
financial instruments are effectively held, if applicable:

N/A



Proxy Voting:

10. Name of the Proxy holder:

N/A



11. Number of voting rights proxy holder will cease to hold:

N/A



12. Date on which proxy holder cease to hold voting rights:

N/A



13. Additional information:

N/A







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