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Antisoma plc (SRC)

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Tuesday 18 July, 2006

Antisoma plc

Directors shareholdings

London, UK: 18 July 2006 - Cancer drug developer Antisoma plc  (LSE:
ASM; USOTC: ATSMY) was notified today of further purchases by
Directors of Antisoma 1p ordinary shares as follows:

                Number of Price/share          Total holding after
                Shares                         purchase

Glyn Edwards    230,000   10.75p
                100,000   11.5p                1,519,962

Raymond Spencer 115,000   11.125p              603,231

Raymond Spencer,
Chief Financial Officer,
+44 (0) 208 799 8200
Antisoma plc