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iSoft Group PLC (IOT)

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Friday 07 April, 2006

iSoft Group PLC

Holding(s) in Company

iSoft Group PLC
07 April 2006



                   NOTIFICATION OF MAJOR INTERESTS IN SHARES



All relevant boxes should be completed in block capital letters

1.       Name of listed company                    2.   Name of shareholder with a major interest


iSOFT Group plc                                    Morgan Stanley Securities Limited


3.       Please state whether notification         4.   Name of the registered holder(s) and, if
indicates that it is regarding the holding of the  more than one holder, the number of shares held by
shareholder named in 2. above; in respect of a     each of them
non-beneficial interest; or in the case of an
individual holder if it is a holding of that
person's spouse or children under the age of 18



Shareholder


5.       Number of       6.       Percentage of    7.   Number of           8.       Percentage of
shares/amount of stock   issued class (any         shares/amount of stock   issued class (any
acquired                 treasury shares held by   disposed                 treasury shares held by
                         the listed company                                 the listed company
                         should not be taken into                           should not be taken into
                         account when calculating                           account when calculating
                         percentage)                                        percentage)


9.       Class of security                             10.    Date of           11.    Date listed
                                                       transaction              company informed


Ordinary Shares of 10p eac                            4th April 2006            7th April 2006

                                                       

12.    Total holding following this notification       13.    Total percentage holding of issued class
                                                       following this notification (any treasury shares
                                                       held by the listed company should not be taken
                                                       into account when calculating percentage)


15,965,398                                             6.87%




14.    Any additional information                    15.    Name of contact and telephone number for
                                                          queries



                                                     Teifion Hill - 0161 490 2706




                      This information is provided by RNS
            The company news service from the London Stock Exchange