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Xenova Group plc (XEN)

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Wednesday 28 April, 2004

Xenova Group plc

Holding(s) in Company

Xenova Group plc
28 April 2004

Notification of interest


In accordance with the provisions of Sections 198-202 of the
Companies Act 1985, we give notice that, as a result of sales of
4,891,989 ordinary shares of 1p each in the relevant share capital of
your company on 27th April 2004, the following client of ISIS Asset
Management Plc has a material interest in the shares shown below:

Name of Client

Isis Inst Inv Funds ICVC Inst UK Smaller Co. Fund

Number of Shares

14,500,351

%

3.36

Name of Registered Holder

Chase Nominees Ltd

This notification supersedes all previous notifications given by
members of the Friends Provident Group in relation to Shares for this
client.


Contact: Douglas Stewart

Tel: 0131 465 2000

From: ISIS Asset Management Plc


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