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British Biotech PLC (VER)

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Monday 06 January, 2003

British Biotech PLC

Director Shareholding

British Biotech PLC
06 January 2003

                                  SCHEDULE 11

          NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS



1. Name of company


British Biotech plc



2. Name of director (1)


Dr Peter Fellner (non-executive Chairman)



3. Please state whether notification indicates that it is in respect of holding
of the shareholder named in 2 above or in respect of a non-beneficial interest
or in the case of an individual holder if it is a holding of that person's
spouse or children under the age of 18 or in respect of a non-beneficial
interest


Notification is in respect of shareholder named at 2 above



4. Name of the registered holder(s) and, if more than one holder, the number of
shares held by each of them (if notified)


Peter Fellner



5. Please state whether notification relates to a person(s) connected with the
director named in 2 above and identify the connected person(s)






6. Please state the nature of the transaction. For PEP transactions please
indicate whether general/single co PEP and if discretionary/non discretionary


Purchase



7. Number of shares / amount of stock acquired


1 million (1,000,000) shares



8. Percentage of issued class


0.15 per cent



9. Number of shares/amount of stock disposed






10. Percentage of issued class






11. Class of security


Ordinary shares



12. Price per share


3.5p



13. Date of transaction


6 January, 2003



14. Date company informed


6 January, 2003



15. Total holding following this notification


1 million (1,000,000) shares



16. Total percentage holding of issued class following this notification


0.15 per cent







2. Name of director (2)


Mr Tim Edwards (acting Chief Executive Officer)



3. Please state whether notification indicates that it is in respect of holding
of the shareholder named in 2 above or in respect of a non-beneficial interest
or in the case of an individual holder if it is a holding of that person's
spouse or children under the age of 18 or in respect of a non-beneficial
interest


Notification is in respect of shareholder named at 2 above



4. Name of the registered holder(s) and, if more than one holder, the number of
shares held by each of them (if notified)


JS&P Nominees Ltd



5. Please state whether notification relates to a person(s) connected with the
director named in 2 above and identify the connected person(s)






6. Please state the nature of the transaction. For PEP transactions please
indicate whether general/single co PEP and if discretionary/non discretionary


Purchase



7. Number of shares / amount of stock acquired


1,188,064 shares



8. Percentage of issued class


0.18 per cent



9. Number of shares/amount of stock disposed






10. Percentage of issued class






11. Class of security


Ordinary shares



12. Price per share


4p



13. Date of transaction


6 January, 2003



14. Date company informed


6 January, 2003



15. Total holding following this notification


1,208,064 shares



16. Total percentage holding of issued class following this notification


0.18 per cent







2. Name of director (3)


Mr Tony Weir (Finance Director)



3. Please state whether notification indicates that it is in respect of holding
of the shareholder named in 2 above or in respect of a non-beneficial interest
or in the case of an individual holder if it is a holding of that person's
spouse or children under the age of 18 or in respect of a non-beneficial
interest


Notification is in respect of shareholder named at 2 above



4. Name of the registered holder(s) and, if more than one holder, the number of
shares held by each of them (if notified)


Tony Weir



5. Please state whether notification relates to a person(s) connected with the
director named in 2 above and identify the connected person(s)






6. Please state the nature of the transaction. For PEP transactions please
indicate whether general/single co PEP and if discretionary/non discretionary


Purchase



7. Number of shares / amount of stock acquired


928,170 shares



8. Percentage of issued class


0.14 per cent



9. Number of shares/amount of stock disposed






10. Percentage of issued class






11. Class of security


Ordinary shares



12. Price per share


4p



13. Date of transaction


6 January, 2003



14. Date company informed


6 January, 2003



15. Total holding following this notification


1,034,610 shares



16. Total percentage holding of issued class following this notification


0.15 per cent







If a director has been granted options by the company please complete the
following boxes.



17. Date of grant






18. Period during which or date on which exercisable






19. Total amount paid (if any) for grant of the option






20. Description of shares or debentures involved: class, number






21. Exercise price (if fixed at time of grant) or indication that price is to be
fixed at time of exercise






22. Total number of shares or debentures over which options held following this
notification






23. Any additional information






24. Name of contact and telephone number for queries


Tony Weir, 01865 781166



25. Name and signature of authorised company official responsible for making
this notification


Stephen Powers, PR Manager, tel 01865 781147



Date of Notification


6 January 2003



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