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XTL Biopharm Ltd (XTL)

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Monday 09 December, 2002

XTL Biopharm Ltd

Holding(s) in Company

XTL Biopharmaceuticals Limited
09 December 2002

                                  SCHEDULE 10

                   NOTIFICATION OF MAJOR INTERESTS IN SHARES

1)       Name of company
         XTL Biopharmaceuticals Limited

2)       Name of shareholder having a major interest
         Perpetual Income & Growth Investment Trust plc

3)       Please state whether notification indicates that it is in respect of holding of the shareholder
         named in 2 above or in respect of a non-beneficial interest or in the case of an individual
         holder if it is a holding of that person's spouse or children under the age of 18
         As 2 above

4)       Name of the registered holder(s) and, if more than one holder, the number of shares held by each
         of them
         Vidacos Nominees Limited

5)       Number of shares/amount of stock acquired
         1,500,000 ordinary shares

6)       Percentage of issued class
         1.35%

7)       Number of shares/amount of stock disposed
         N/A

8)       Percentage of issued class
         N/A

9)       Class of security
         Ordinary shares of IIs0.02 each

10)      Date of transaction
         4 December 2002

11)      Date company informed
         5 December 2002

12)      Total holding following this notification
         4,410,215 shares

13)      Total percentage holding of issued class following this notification
         3.974%

14)      Any additional information


15)      Name of contact and telephone number for queries
         Jonathan Burgin, Chief Financial Officer +972 (0) 894 05134

16)      Name and signature of authorised company official responsible for making this notification
         Jonathan Burgin

17)      Date of notification
         9 December 2002


                      This information is provided by RNS
            The company news service from the London Stock Exchange