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Xenova Group PLC (XEN)

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Friday 01 June, 2001

Xenova Group PLC

Holding in Company

Xenova Group PLC
31 May 2001



LETTER TO XENOVA GROUP PLC
DATED:  29 MAY 2001

Companies Act 1985 (as amended):
Disclosure of Interests in Shares

In accordance with Part VI of the Companies Act 1985 (as amended) (the 'Act'),
we write to inform you that Prudential Plc and certain of its subsidiary
companies have a notifiable interest in the issued share capital of your company
as detailed in the schedule below.

For the purposes of s210 of the Act, the address for those companies identified
in the schedule below is Laurence Pountney Hill London EC4R OHH.

          Notifiable Position Report for XENOVA GROUP ORD GBP0.10
                      as at 28 MAY 2001
  
Percentage Holdings are calculated using an issued share capital of 139,190,000
ORD GBP 0.10 shares
                   
                Registered Holder                 Holding      %
Prudential plc                                   7,519,246    5.40   Total      
                                                                    Notifiable  
                                                                     Interest 
               PRUCLT HSBC GIS NOM(UK) PAC AC    6,054,285
               PRUCLT HSBC GIS NOM(UK) PPL AC    1,464,961

The Prudential Assurance
Company Limited                                  7,519,246    5.40
               
               PRUCLT HSBC GIS NOM(UK) PAC AC    6,054,285
               PRUCLT HSBC GIS NOM(UK) PPL AC    1,464,961

FROM M&G INVESTMENT MANAGEMENT LIMITED