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Xenova Group PLC (XEN)

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Wednesday 02 May, 2001

Xenova Group PLC

Holding in Company

Xenova Group PLC
2 May 2001


LETTER TO:  XENOVA GROUP PLC
DATED:      30 April 2001

Companies Act 1985 (as amended):
Disclosure of Interests in Shares

In accordance with Part VI of the Companies Act 1985 (as amended) (the 'Act'),
we write to inform you that Prudential plc and certain of its subsidiary
companies have a notifiable interest in the issued share capital of your company
as detailed below.

For the purposes of S210 of the Act, the address for those companies identified
in the below schedule is Laurence Pountney Hill London EC4R 0HH.

LETTER FROM:  Tom Dowler
              for and on behalf of Prudential plc



             Notifiable Position Report for XENOVA GROUP ORD GBP0.10
                               as at 27 April 2001

Percentage holdings are calculated using an issued share capital of 139,190,000
ORD GBP0.10 shares

               Registered Holder                 Holding    %   Total Notifiable
                                                                    Interest
Prudential plc                                 5,810,245  4.17


               PRUCLT HSBC GIS NOM (UK) PAC AC 4,345,284

               PRUCLT HSBC GIS NOM (UK) PPL AC 1,464,961


The Prudential Assurance Company Limited       5,810,245  4.17

               PRUCLT HSBC GIS NOM (UK) PAC AC 4,345,284

               PRUCLT HSBC GIS NOM (UK) PPL AC 1,464,961