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Xenova Group PLC (XEN)

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Tuesday 10 April, 2001

Xenova Group PLC

Holding in Company

Xenova Group PLC
10 April 2001



LETTER TO XENOVA GROUP PLC - DATED 9th APRIL 2001

SECTION 198 COMPANIES ACT 1985 ('THE ACT')

We write in accordance with the above Act to advise you that, following the
exchange of 445,942 shares in Cantab Pharmaceuticals plc for 700,766 Ordinary
Shares of 10p each in Xenova Group plc, this Company is the beneficial owner of
3,015,159 Ordinary Shares of 10p each in your Company, representing 4.35%*.  The
shares are registered in the name of Chase Nominees Limited


* Based on an issued share capital of 69,253,305

FROM INVESCO ENGLISH AND INTERNATIONAL TRUST PLC