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Xenova Group PLC (XEN)

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Tuesday 15 August, 2000

Xenova Group PLC

Holding in Company

Xenova Group PLC
15 August 2000

LETTER TO:  XENOVA GROUP PLC  Dated:  11 August 2000

Companies Act 1985 
Disclosures of Interest in Voting Shares

In compliance with Part VI of the above Act, as amended, I inform you that, as a
result of a recent conversion, the notifiable interest of Prudential plc
(together with that of the funds which we manage for clients), in the following
class of voting share in you company, is now as specified below.

LETTER FROM: Tom Dowler 
             for and on behalf of Prudential plc

SEDOL:  0985000    Client Fund Reporting Group:  PPMI

            Shares in Issue  Registered Holder     Current Holding  Holding
ORD GBP0.10    69,242,577     CHASE NOMS LT
                              A/C 14914               175,160

                              CHASE NOMS LTD 
                              A/C 14922               291,935

                              CLYDESDALE BK (H.OFF)
                              NOMS LTD                291,935
                              CLYDESDALE BK NOMS LTD 
                              MGA                     408,710

                              CLYDESDALE BK NOMS LTD
                              MGC                   3,785,648                   
                              M&G INNOVATOR FUND      350,320

                              PRUCLT HSBC GIS NOM
                              (UK) PPL AC           1,842,961

              69,242,577                            7,146,669      10.32