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Xenova Group PLC (XEN)

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Friday 11 August, 2000

Xenova Group PLC

Holding in Company

Xenova Group PLC
11 August 2000

Letter to:  Xenova Group plc

Section 198 Companies Act 1985 ('The Act')

We write in accordance with the above Act to advise you that, following the
placing and open offer, this Company is the beneficial owner of 2,314,393
Ordinary Shares of 10p each in your Company, representing 3.34%*.  The shares
are registered in the name of Chase Nominees Limited.

* Based on an issued share capital of 69,242,577

Letter from:  Invesco English and International Trust plc