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Xenova Group PLC (XEN)

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Tuesday 08 August, 2000

Xenova Group PLC

Holding in Company

Xenova Group PLC
8 August 2000

LETTER TO:  XENOVA GROUP PLC
7 August 2000

Part VI Companies Act 1985

We hereby notify you in accordance with Part VI Companies Act 1985 ('the Act')
that HSBC Investment Bank plc was at the close of business on 3 August 2000
interested in 1,980,000 ordinary shares of Xenova Group plc ('the Shares').  Of
these interests, 1,730,000 were interests of a kind described in S.208(5) of the
Act.

HSBC Investment Bank Holdings plc as HSBC Investment Bank plc's parent and HSBC
Holdings plc, our ultimate parent company, were also interested by virtue of
S.203 of the Act in all of the above mentioned Shares.

LETTER FROM:  David Cooper (Head of Securities Compliance, HSBC Investment Bank 
             Plc)