Board Appointment

Evolutec Group PLC 23 May 2006 For immediate release 23 May 2006 EVOLUTEC GROUP PLC ('Evolutec' or 'the Company') Appointment of Non-Executive Director Evolutec Group plc (AIM: EVC), the biopharmaceutical company developing novel products for the treatment of allergic, inflammatory and autoimmune diseases, is pleased to announce the appointment of Malcolm Lawton Darvell as a Non-Executive Director, effective from 24 May 2006. Mr Darvell, aged 43, is currently the Chief Executive of Rontech Limited, a privately held company that develops software for the global financial services industry. Mr Darvell has experience in both the financial and biotechnology sectors. He was previously Chief Financial Officer of Tempest Consultants Limited, a company involved in equity market surveys, of Azur Environmental Limited, a company supplying environmental monitoring equipment, and of Peptech Limited, the Australian listed biotechnology company. Prior to that, Mr Darvell was Head of Corporate Finance Advisory at Nomura International and was instrumental in building that franchise. There are no further disclosures to be made in accordance with Schedule 2 (g) of the AIM rules. David Bloxham, Evolutec's Chairman, said: 'I welcome Malcolm to Evolutec's Board, where his financial knowledge and experience of growing smaller companies will be of great value as Evolutec progresses to the next stage in the Company's development.' For further information: Evolutec Group plc Tel: 0118 922 4480 Mark Carnegie Brown, Chief Executive Officer Nicholas Badman, Chief Financial Officer www.evolutec.co.uk Buchanan Communications Tel: 020 7466 5000 Mark Court/Mary-Jane Johnson/Catherine Breen Notes for Editors: About Evolutec Group plc Evolutec is a biopharmaceutical company developing drugs for allergy, inflammation and autoimmune disease. Evolutec's lead drug candidate, rEV131 has efficacy in both acute and chronic respiratory indications including allergic rhinitis (hay fever) and asthma. In 2005, Evolutec announced a positive result for rEV131 in a 112 patient Phase IIa proof of concept study in allergic rhinitis. rEV131 met the primary efficacy endpoint (p < 0.05). In addition, rEV131 showed efficacy against mucus and congestion, the most difficult to treat symptoms of rhinitis as well as a rapid onset of action. Evolutec intends to carry out additional proof of concept Phase II trials with rEV131 in post-cataract surgery and dry eye. Positive preclinical data has also been generated in asthma. rEV131 is a histamine binding protein and is understood to be the only product currently in clinical trials that impacts the recently discovered H4 receptor, a receptor implicated in many forms of inflammatory disease. The Company has a further two molecules in preclinical development. rEV576, a complement inhibitor that was very effective in a preclinical model of myasthenia gravis, and rEV598, which is being evaluated in carcinoid syndrome and CINV (chemotherapy-induced nausea and vomiting). Evolutec is working with Merial to develop anti-tick and anti-tick borne disease vaccines. Evolutec, which is based in Reading, UK, was founded in 1998 to exploit research carried out by the Natural Environment Research Council. Evolutec's drugs were first isolated from the saliva of ticks but are now manufactured by bacterial fermentation procedures. The tick remains undetected by its hosts, including humans, by injecting an array of molecules into the skin that suppresses normal defence mechanisms. These stealth molecules have evolved over millions of years to enable the tick to take a blood meal from its host. Evolutec employs the tick's evolutionary stealth technology to offer the potential of treating human diseases. Safe Harbour statement: this news release may contain forward-looking statements that reflect the current expectations of the Company regarding future events. Forward-looking statements involve risks and uncertainties. Actual events could differ materially from those projected herein and depend on a number of factors including the success of the Company's research strategies, the applicability of the discoveries made therein, the successful and timely completion of clinical studies, the uncertainties related to the regulatory process, the successful integration of completed mergers and acquisitions and achievement of expected synergies from such transactions, and the ability of the Company to identify and consummate suitable strategic and business combination transactions. This information is provided by RNS The company news service from the London Stock Exchange
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