Director Shareholding

GlaxoSmithKline PLC
30 April 2001

                             Directors' Interests


I give below details of a change in the interests in Ordinary Share ADRs of
GlaxoSmithKline plc (each ADR represents two Ordinary Shares) in respect of
the undermentioned Director arising from the purchase of Ordinary Share ADRs
on 27 April 2001 through the monthly investment element of the US Global
BuyDirect Plan administered by The Bank of New York, which Mr McArthur entered
on 4 May 1997:-


Mr J H         Beneficial interest in 279.8756 Ordinary Share ADRs purchased at
McArthur       a price of US$ 53.520 per ADR.



Mr McArthur and the Company were advised of this information on 27 April 2001.


S M Bicknell

30 April 2001