Acquisition

Provalis PLC 4 December 2001 For Immediate Release 4 December 2001 Provalis plc Completion of the Acquisition of Diclomax(R) Products From Parke-Davis (Pfizer) Provalis plc, the integrated healthcare company, is pleased to announce that its acquisition of the trademarks, UK marketing licences, goodwill and stocks of the Diclomax products from Parke-Davis & Co Limited (PD), a subsidiary of Pfizer Inc, was approved at it's Extraordinary General Meeting held yesterday, with 99% of those shareholders who voted voting in favour. Following this approval from shareholders, the acquisition was completed after close of business yesterday. As announced on 25th October 2001, the total cash consideration payable by Provalis will be £14.5 million, payable by means of an initial instalment of £ 1.9 million, with the balance of £12.6 million payable over 3 years. There will also be a further payment of up to £0.8 million for stocks. Phil Gould, CEO of Provalis said, 'We are very pleased that the acquisition of the Diclomax products, which is a landmark deal for Provalis, received such over-whelming support from our shareholders. These products, which had aggregate sales of £6.7 million in the year to 31 December 2000, will almost double the turnover of our Healthcare division, will significantly increase our Group revenues and will improve our margins. Following completion of the acquisition yesterday evening, we will now begin selling these products to our customers today.' END Provalis' Internet Website ; http://www.provalis.com N M Rothschild & Sons Limited, which is regulated in the UK by The Financial Services Authority, is acting as financial adviser to Provalis and no-one else in relation to this Acquisition and will not be responsible to anyone other than Provalis for providing the protections afforded to its customers or for providing advice in relation to the proposed Acquisition. 'Safe Harbor' Statement under the US Private Securities Litigation Reform Act of 1995: Statements in this announcement that relate to future plans, expectations, events, performances and the like are forward-looking statements as defined in the US Private Securities Litigation Reform Act of 1995. Actual results of events could differ materially from those described in the forward-looking statements due to a variety of factors. Such factors include, among others: the success of the Group's research and development strategy; uncertainties related to future trial results and the regulatory process; the execution and success of collaborative agreements with third parties; the impact of future laws, regulations and policies; the Group's intellectual property position and the success of patent applications for its products and technologies; stock market trends in the Group's sector; the Group's dependence on key personnel; general business and economic conditions; and other factors beyond the Group's control that may cause the Group's available capital resources to be used more quickly than expected. These and other factors that could affect the Company's future results are more fully described in its filings with the US Securities and Exchange Commission, in particular the latest 20-F filing, copies of which are available from the Company Secretary at the Company's registered address. For further information:- Dr Phil Gould, Chief Executive, Provalis plc, Tel: 01244 833463 Mr Neil Kirkby, Finance Director, Provalis plc, Tel: 01244 833552 Lisa Baderoon, Buchanan Communications, Tel: 020 7466 5000 David Forbes, N M Rothschild & Sons Ltd, Tel: 0113 200 1900 Corporate and Public Affairs, Pfizer Limited, Tel: 01304 616161 Notes to Editors Provalis plc (LSE.PRO and NASDAQ.PVLS) is an integrated healthcare company with three separate divisions: Healthcare - This division sells and markets branded, third party, prescription medicines in the UK to GPs and hospitals through its own regionally managed 42 man sales force. This division sells products in the areas of gastroenterology, muscular-skeletal disorders, osteoporosis, migraine and osteoarthritis. Medical Diagnostics - This division develops and sells medical diagnostic products to world markets through distributors. The division has an established business in diagnostic products for infectious diseases and has recently launched the innovative products GlycosalTM and OsteosalTM in the areas of diabetes and osteoporosis respectively. Therapeutic R&D - This division develops a range of vaccine candidates for infectious diseases through a network of research collaborators. The Diclomax(R) Products The Diclomax products have been available on the UK market since 1992, and are licensed for the treatment of osteoarthritis, rheumatoid arthritis, acute joint pain, strains and sprains, and pain and inflammation in orthopaedic, dental and other minor surgery. The segment of the UK pharmaceutical market in which Diclomax competes is currently worth £220 million per annum. Diclofenac itself is a well established NSAID agent and has been on the UK market for over 20 years. Diclofenac products had UK retail sales of over £80 million in 2000. The Diclomax products are currently sold by Parke-Davis & Co Limited, a subsidiary of Pfizer Inc, to pharmaceutical wholesalers who supply pharmacies and hospitals in the UK. The products are only available on prescription from doctors and consultants in the UK. Pfizer Pfizer, with its headquarters in New York, is a research-based global pharmaceutical company. Pfizer discovers, develops, manufactures and markets leading prescription medicines for humans and animals, and many of the world's best known consumer products. Since 1990 Pfizer has invested over £1 billion in the UK and is one of the top three suppliers of medicines to the NHS.

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