Offer Update

Billam PLC 9 November 2001 Not for release, publication or distribution in, into or from the United States, Canada, Australia or Japan 9 November 2001 Billam Plc ('Billam') Recommended Offer by Peel Hunt plc ('Peel Hunt') on behalf of Billam Plc for World Life Sciences plc ('WLS') First Closing date Offer unconditional in all respects and extended until further notice On 18 October 2001, a recommended offer was made by Peel Hunt, on behalf of Billam, for the entire issued share capital of WLS (other than that already owned or controlled by Billam) (the 'Offer'), as set out in the Offer Document dated 18 October 2001. The board of Billam announces that by 3.00 p.m. on 8 November 2001, the first closing date of the Offer, Billam had received valid acceptances in respect of a total of 278,333,042 WLS Shares (representing approximately 36.3 per cent. of the existing issued ordinary share capital of WLS and approximately 62.4 per cent of the WLS Shares to which the Offer relates). These figures include all acceptances received from persons acting in concert with Billam and all acceptances received from persons that had irrevocably undertaken to accept the Offer. The Offer is now declared unconditional as to acceptances and will remain open for acceptances until further notice. The board of Billam further announces that all other conditions to the Offer have now either been satisfied or waived, subject only to the admission of the new Billam Shares to trading on AIM becoming effective ('Admission'). Accordingly the Offer is declared unconditional in all respects subject only to such Admission. Application for Admission has been made in respect of the 208,749,738 Billam Shares being issued as consideration to WLS Shareholders who have validly accepted the Offer, and such Admission is expected to become effective at 8.00 a.m. on 14 November 2001. Billam intends to procure that WLS applies to the London Stock Exchange for WLS Shares to be de-listed from AIM as of 8.00 a.m. on 14 November 2001. Prior to the Offer being made, Billam owned 320,000,000 WLS Shares through its wholly owned subsidiary Billam AG, representing 41.8 per cent. of the existing ordinary share capital of WLS. In addition, Billam received irrevocable undertakings from the directors of and the consultant to WLS to accept the Offer in respect of shareholdings which amounted, in aggregate, to 69,662,000 WLS Shares, representing approximately 9.1 per cent. of the existing issued ordinary share capital of WLS. Billam has now received acceptances for all 69,662,000 of these WLS Shares (and these acceptances are included in the acceptances referred to above). In total, therefore, as at 18 October 2001, Billam held or had received irrevocable undertakings to accept the Offer in respect of 389,662,000 WLS Shares, representing approximately 50.9 per cent, of the existing ordinary share capital of WLS. As at 18 October 2001, persons acting in concert with Billam (as defined by the Code), other than those persons that gave Billam irrevocable undertakings to accept the Offer, held 900,000 WLS Shares, representing 0.1 per cent. of the existing ordinary share capital of WLS. Billam has received acceptances in respect of all 900,000 of these WLS Shares (and these acceptances are included in the acceptances referred to above). Save as disclosed above, neither Billam, nor any person acting in concert or deemed to be acting in concert with Billam held any WLS Shares (or rights over such shares) prior to the commencement of the Offer Period or has acquired or agreed to acquire any WLS Shares (or rights over such shares) during the Offer Period and no acceptance of the Offer has been received from any person acting in concert with Billam. The expressions used in this announcement shall, unless the context otherwise requires, bear the same meanings as set out in the Offer Document dated 18 October 2001. Enquiries: Angus Forrest - Billam Plc: 020 7702 5544 The directors of Billam accept responsibility for the information contained in this announcement. To the best of the knowledge and belief of the directors of Billam (who have taken all reasonable care to ensure such is the case), the information contained herein for which they accept responsibility is in accordance with the facts and does not omit anything likely to affect the import of such information. Peel Hunt is acting for Billam in relation to the Offer and is not acting for any other person and will not be responsible to any other person for providing the protections afforded to customers of Peel Hunt or for advising them on any other matter in relation to the Offer.

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