Spinal Surgery Trial Results

Deltex Medical Group PLC 26 September 2006 Deltex Medical Group plc French clinical trial demonstrates utility of CardioQ(TM) in spinal surgery 26 September 2006 Deltex Medical Group plc ('Deltex Medical' or the 'Company'), the UK's leading haemodynamic monitoring company, today highlights the presentation of a clinical trial undertaken by Dr Payen and colleagues at Grenoble hospital into the use of Deltex Medical's CardioQ monitor. The trial results were made public at the European Society of Intensive Care Medicine (ESICM) conference in Barcelona earlier today. Patients undergoing spinal surgery are placed face down on the operating table ('prone position') throughout the surgery. The prone position can have an adverse effect on the patient's blood circulation ('haemodynamics') and potentially lead to complications. It is therefore important to be able to identify and treat any haemodynamic changes in these patients quickly and safely. The trial results showed that it is possible to monitor patients having spinal surgery in the prone position effectively and safely using the minimally invasive CardioQ. Deltex Medical's chief executive, Andy Hill, commented: 'This trial confirms for the first time that the CardioQ works in spinal surgery - where rapid diagnosis and intervention is required to prevent potentially life-threatening complications. Multiple randomised trials have demonstrated that the CardioQ is the only intra-operative haemodynamic monitor which can reduce complications and length of hospital stay.' For further information, please contact:- Deltex Medical Group plc 01243 774 837 Nigel Keen, Nigel Chairman Andy Hill, Chief Executive Ewan Phillips, Finance Director Gavin Anderson & Company 0207 554 1400 Deborah Walter Marie Cairney Jodie Reilly Charles Stanley Securities 020 7149 6457 Philip Davies Notes for Editors Deltex Medical manufactures and markets the CardioQ monitor, which uses disposable ultra-sound probes inserted into the oesophagus to determine the amount of blood being pumped around the body - 'circulating blood volume'. Reduced circulating blood volume is known as hypovolaemia, which leads to insufficient oxygen being delivered to the organs. This causes medical complications including peripheral and major organ failure which can lead to death. Hypovolaemia, which is akin to severe dehydration, affects virtually every patient having surgery because of the combined effects of pre-operative starvation, the impact of the anaesthetic agents and trauma from the surgery itself. Using fluids and drugs, guided by the CardioQ, to optimise the amount of circulating blood significantly reduces post-operative complications allowing patients to make a faster, more complete recovery and return home earlier. The CardioQ incorporates the Company's proprietary software and a small diameter, easy-to-use, minimally invasive, disposable oesophageal probe that is used for transmitting and receiving an ultra-sound signal. By using this technology, the CardioQ provides clinicians with the ability to haemodynamically optimise critically ill patients and those undergoing routine moderate to major surgery through the controlled administration of fluid and drugs. Haemodynamic optimisation has been scientifically proven to improve the speed and quality of patient recovery and reduce hospital stay. There are already over 1,250 CardioQs currently in use in hospitals worldwide and distribution arrangements are in place in over 30 countries. In addition, there are currently more than 90 clinical publications on the use of the CardioQ which have repeatedly:- • Validated the results of the Monitor against known standards for measuring cardiac output, demonstrating that the technology works • Proved that the CardioQ works in a wide range of surgical procedures • Demonstrated that the Company's technology provides significant health and economic benefits by helping to reduce post-operative complications and length of hospital stays by an average of 30 to 40 per cent for a wide range of patients. This information is provided by RNS The company news service from the London Stock Exchange
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