Re Research Study

Deltex Medical Group PLC 12 July 2004 12 July 2004 Deltex Medical Group plc Nurse-led randomised trial demonstrates significant reduction in hospital length of stay through use of CardioQ on patients following cardiac surgery Deltex Medical Group plc ('Deltex Medical' / 'Company'), the AIM listed haemodynamic monitoring company, today announces the publication of the results of a randomised controlled clinical trial assessing the impact of the use by nurses of its CardioQ haemodynamic monitor on patients in intensive care and cardiothoracic units following cardiac surgery. The study, published by the British Medical Journal on 8 July 2004, concluded that patients whose circulatory status was optimised using the CardioQ were able to leave hospital two days earlier than those whose treatment was managed traditionally. The study also demonstrated a 23% reduction in length of stay in intensive care - by far the most costly part of a patient's stay in hospital outside of the operating theatre. This trial was undertaken by nurses on patients at the University College of London hospitals in London, working in conjunction with Professor Mervyn Singer and using treatment protocols developed by medical and nursing staff. Chief Executive, Andy Hill, commented: 'Once again an independent trial has clearly demonstrated that using the CardioQ to optimise patient's haemodynamic status following surgery improves patient outcomes and thereby creates an opportunity to realise significant economic benefits for health care providers. 'Empowering nurses to use this approach to patient management is an important step towards delivering better care for more patients in the National Health Service. I fully expect this result to further accelerate the adoption of nurse-led, protocol driven haemodynamic optimisation across the NHS.' For further information, please contact:- Deltex Medical Group plc Nigel Keen, Chairman nigel.keen@deltexmedical.com 01243 774 837 Andy Hill, Chief Executive andy.hill@deltexmedical.com 01243 774 837 Ewan Phillips, Finance Director ewan.phillips@deltexmedical.com 01243 774 837 Financial Dynamics Stephanie Highett stephanie.highett@fd.com 020 7831 3113 Notes for Editors Deltex Medical manufactures and markets the CardioQ monitor, which uses disposable ultra-sound probes inserted into the oesophagus to determine the amount of blood being pumped around the body - 'circulating blood volume'. Reduced circulating blood volume is known as hypovolemia, which leads to insufficient oxygen being delivered to the organs. This causes medical complications including peripheral and major organ failure which can lead to death. Hypovolemia, which is akin to severe dehydration, affects virtually every patient having surgery because of the combined effects of pre-operative starvation, the impact of the anaesthetic agents and trauma from the surgery itself. Using fluids and drugs, guided by the CardioQ, to optimise the amount of circulating blood significantly reduces post-operative complications allowing patients to make a faster, more complete recovery and return home earlier. The CardioQ incorporates the Company's proprietary software and a small diameter, easy-to-use, minimally invasive, disposable oesophageal probe that is used for transmitting and receiving an ultra-sound signal. By using this technology, the CardioQ provides clinicians with the ability to haemodynamically optimise critically ill patients and those undergoing routine moderate to major surgery through the controlled administration of fluid and drugs. Haemodynamic optimisation has been scientifically proven to improve the speed and quality of patient recovery and reduce hospital stay. There are over 1,250 CardioQs currently in use in hospitals worldwide and distribution arrangements are in place in over 30 countries. In addition, there are currently more than 90 clinical publications on the use of the CardioQ which have repeatedly:- • validated the results of the Monitor against known standards for measuring cardiac output, demonstrating that the technology works • proved that the CardioQ works in a wide range of surgical procedures • demonstrated that the Company's technology provides significant health and economic benefits by helping to reduce post-operative complications and length of hospital stays by an average of 30 to 40 per cent for a wide range of patients. This information is provided by RNS The company news service from the London Stock Exchange
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