NICE Review

Deltex Medical Group PLC 14 February 2006 Deltex Medical Group plc NICE assesses CardioQ as standard clinical practice Tuesday 14 February 2006: Deltex Medical Group plc ('Deltex Medical' or the 'Company'), the AIM listed haemodynamic monitoring company, today announces the results of a NICE ('National Institute of Clinical Excellence') review of the technique of oesophageal Doppler monitoring ('ODM'). NICE's review concluded that the CardioQ does not require further approval by NICE. NICE has confirmed that 'oesophageal Doppler monitoring is considered standard clinical practice.' The NICE review, under its Interventional Procedures Programme, involved consultation with clinical experts nominated by the Association of Anaesthetists of Great Britain and Ireland and the Intensive Care Society. The review also included a study of the extensive body of published clinical evidence on the technique of ODM. The vast majority of clinical data on ODM comprises studies which used the Company's CardioQ monitors or predecessor devices. NICE is the UK government department responsible for assessing the safety and efficacy of new medical technologies under its Interventional Procedures Programme. If NICE concludes that a new technology falls within its remit under the Interventional Procedures Programme, it will go on to develop guidance on the safety and efficacy of that procedure. The development of such guidance can take a considerable amount of time, especially as NICE has an extensive backlog of cases to review. NICE can require that every doctor using a new technology in the NHS records and reports its every use during the review process. During the NICE review process NHS Trusts may prefer not to purchase the technology under review pending publication of the results of the NICE evaluation. Nigel Keen, Deltex Medical's Chairman, commented: 'NICE's acknowledgment that use of the CardioQ is considered to be a standard clinical practice in the UK NHS is a significant step forward for the Company, as it gives the doctors seeking to purchase our products additional support when making purchasing requests from the hospital finance managers. 'Oesophageal Doppler monitoring is the only cardiac output monitoring technology to have been assessed as standard clinical practice by NICE. This further differentiates our products which are safer and more efficacious than traditional and alternative technologies as well as being more effective clinically, better evidenced and less expensive.' For further information, please contact:- Deltex Medical Group plc 01243 774 837 Nigel Keen, Chairman nigel.keen@deltexmedical.com Andy Hill, Chief andy.hill@deltexmedical.com Executive Ewan Phillips, ewan.phillips@deltexmedical.com Finance Director Financial Dynamics 0207 831 3113 David Yates david.Yates@fd.com John Gilbert john.gilbert@fd.com Notes for Editors Deltex Medical manufactures and markets the CardioQ monitor, which uses disposable ultra-sound probes inserted into the oesophagus to determine the amount of blood being pumped around the body - 'circulating blood volume'. Reduced circulating blood volume is known as hypovolaemia, which leads to insufficient oxygen being delivered to the organs. This causes medical complications including peripheral and major organ failure which can lead to death. Hypovolaemia, which is akin to severe dehydration, affects virtually every patient having surgery because of the combined effects of pre-operative starvation, the impact of the anaesthetic agents and trauma from the surgery itself. Using fluids and drugs, guided by the CardioQ, to optimise the amount of circulating blood significantly reduces post-operative complications allowing patients to make a faster, more complete recovery and return home earlier. The CardioQ incorporates the Company's proprietary software and a small diameter, easy-to-use, minimally invasive, disposable oesophageal probe that is used for transmitting and receiving an ultra-sound signal. By using this technology, the CardioQ provides clinicians with the ability to haemodynamically optimise critically ill patients and those undergoing routine moderate to major surgery through the controlled administration of fluid and drugs. Haemodynamic optimisation has been scientifically proven to improve the speed and quality of patient recovery and reduce hospital stay. There are already over 1,250 CardioQs currently in use in hospitals worldwide and distribution arrangements are in place in over 30 countries. In addition, there are currently more than 90 clinical publications on the use of the CardioQ which have repeatedly:- • validated the results of the Monitor against known standards for measuring cardiac output, demonstrating that the technology works • proved that the CardioQ works in a wide range of surgical procedures • demonstrated that the Company's technology provides significant health and economic benefits by helping to reduce post-operative complications and length of hospital stays by an average of 30 to 40 per cent for a wide range of patients. This information is provided by RNS The company news service from the London Stock Exchange
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