New Clinical Evidence

Deltex Medical Group PLC 28 June 2007 Deltex Medical Group plc International endorsement of CardioQTM for critically ill children 28 June 2007 - Deltex Medical Group plc ('Deltex Medical' or 'Company'), the UK's leading haemodynamic monitoring company, today announces new clinical evidence of the value of its CardioQPTM monitoring system for the treatment of young children in intensive care units. The results of four studies using CardioQP in hospitals in France, the UK and Brazil were presented this week to international doctors at the 5th World Congress on Paediatric Critical Care in Geneva, Switzerland. Doctors from the Hopital Arnaud de Villeneuve in Montpellier, France reported that they had found the CardioQP to be an excellent predictor of the fluid-responsiveness in children with low blood pressure. Paediatric intensive care specialists from Sao Paulo, Brazil concluded that the CardioQP 'was extremely important in the evaluation and (management) of patients with septic shock' particularly given 'the limited forms of measuring haemodynamic variables in paediatric intensive care units in low-income countries.' A team from Birmingham Children's Hospital in the UK concluded in their study 'that clinical assessment of cardiac output and systemic vascular resistance are frequently unreliable' with doctors' own assessments agreeing with CardioQP measurements only approximately half the time. In a second study on 20 children in intensive care, the clinical management strategy was changed in eight of the nine cases where CardioQP data differed from the original clinical assessment. Deltex Medical's Chief Executive, Andy Hill commented: 'These studies reinforce the strengths of the CardioQP in the monitoring and treatment of very sick children. It is safe, accurate, affordable and easy to use: it allows doctors to assess childrens' haemodynamic status quickly and make better-informed clinical decisions. 'This new clinical evidence supports further our belief that the CardioQP ought to be made available to all doctors treating critically ill children.' For further information, please contact:- Deltex Medical Group plc 01243 774 837 Nigel Keen, Chairman njk@deltexmedical.com Andy Hill, Chief Executive ahill@deltexmedical.com Ewan Phillips, Finance Director eap@deltexmedical.com Gavin Anderson & Company 020 7554 1400 Deborah Walter dwalter@gavinanderson.co.uk Robert Speed rspeed@gavinanderson.co.uk Charles Stanley Securities 020 7149 6457 Philip Davies philip.davies@csysecurities.com Russell Cook russell.cook@csysecurities.com Notes for Editors Deltex Medical manufactures and markets the CardioQ monitor, which uses disposable ultra-sound probes inserted into the oesophagus to determine the amount of blood being pumped around the body - 'circulating blood volume'. Reduced circulating blood volume is known as hypovolaemia, which leads to insufficient oxygen being delivered to the organs. This causes medical complications including peripheral and major organ failure which can lead to death. Hypovolaemia, which is akin to severe dehydration, affects virtually every patient having surgery because of the combined effects of pre-operative starvation, the impact of the anaesthetic agents and trauma from the surgery itself. Using fluids and drugs, guided by the CardioQ, to optimise the amount of circulating blood significantly reduces post-operative complications allowing patients to make a faster, more complete recovery and return home earlier. The CardioQ incorporates the Company's proprietary software and a small diameter, easy-to-use, minimally invasive, disposable oesophageal probe that is used for transmitting and receiving an ultra-sound signal. By using this technology, the CardioQ provides clinicians with the ability to haemodynamically optimise critically ill patients and those undergoing routine moderate to major surgery through the controlled administration of fluid and drugs. Haemodynamic optimisation has been scientifically proven to improve the speed and quality of patient recovery and reduce hospital stay. There are already over 1,250 CardioQs currently in use in hospitals worldwide and distribution arrangements are in place in over 30 countries. In addition, there are currently more than 90 clinical publications on the use of the CardioQ which have repeatedly:- •Validated the results of the Monitor against known standards for measuring cardiac output, demonstrating that the technology works •Proved that the CardioQ works in a wide range of surgical procedures •Demonstrated that the Company's technology provides significant health and economic benefits by helping to reduce post-operative complications and length of hospital stays by an average of 30 to 40 per cent for a wide range of patients. The SupraQ is an entirely non-invasive device which uses an ultrasound probe held at the base of the patient's neck to track the flow of blood in the aorta; it presents the same data as the CardioQ in a similar format and is used for taking snapshots or monitoring over short periods. This information is provided by RNS The company news service from the London Stock Exchange
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