Director/PDMR Shareholding

Cambridge Antibody Tech Group PLC
30 December 2005

NOTIFICATION OF TRANSACTIONS OF DIRECTORS, PERSONS DISCHARGING MANAGERIAL
RESPONSIBILITY OR CONNECTED PERSONS

This form is intended for use by an issuer to make a RIS notification required
by DR 3.1.4R(1).


(1)   An issuer making a notification in respect of a transaction relating to
      the shares or debentures of the issuer should complete boxes 1 to 16, 23
      and 24.
(2)   An issuer making a notification in respect of a derivative relating the
      shares of the issuer should complete boxes 1 to 4, 6, 8,13, 14, 16, 23 and
      24.
(3)   An issuer making a notification in respect of options granted to a
      director/person discharging managerial responsibilities should complete
      boxes 1 to 3 and 17 to 24.
(4)   An issuer making a notification in respect of a financial instrument
      relating to the shares of the issuer (other than a debenture) should
      complete boxes 1 to 4, 6, 8, 9, 11, 13, 14, 16, 23 and 24.



Please complete all relevant boxes should in block capital letters.



1. Name of the issuer



Cambridge Antibody Technology Group plc



2. State whether the notification relates to (i) a transaction notified in
accordance with DR 3.1.4R(1)(a); or

(ii) DR 3.1.4(R)(1)(b) a disclosure made in accordance with section 324 (as
extended by section 328) of the Companies Act 1985; or

(iii) both (i) and (ii)

(ii)



3. Name of person discharging managerial responsibilities/director



John Aston



4. State whether notification relates to a person connected with a person
discharging managerial responsibilities/director named in 3 and identify the
connected person



As in 3. above



5. Indicate whether the notification is in respect of a holding of the person
referred to in 3 or 4 above or in respect of a non-beneficial interest



As in 3. above



6. Description of shares (including class), debentures or derivatives or
financial instruments relating to shares



Ordinary 10 Pence Shares



7. Name of registered shareholders(s) and, if more than one, the number of
shares held by each of them



Greenwood Nominees Limited



8 State the nature of the transaction



Allotment and issue of new shares in the Company issued at the average mid
market quotation as derived from the Daily Official List for the three business
days preceding 30 December 2005 such shares having been acquired for the purpose
of the Matching Share element of the Executive Incentive Plan.



9. Number of shares, debentures or financial instruments relating to shares
acquired



3,816



10. Percentage of issued class acquired (treasury shares of that class should
not be taken into account when calculating percentage)



0.007%



11. Number of shares, debentures or financial instruments relating to shares
disposed



NIL



12. Percentage of issued class disposed (treasury shares of that class should
not be taken into account when calculating percentage)



N/A



13. Price per share or value of transaction



£6.976



14. Date and place of transaction



30 December 2005



15. Total holding following notification and total percentage holding following
notification (any treasury shares should not be taken into account when
calculating percentage)



76,556



16. Date issuer informed of transaction



30 December 2005



If a person discharging managerial responsibilities has been granted options by
the issuer complete the following boxes



17 Date of grant



30 December 2005



18. Period during which or date on which it can be exercised



30 December 2008 to 29 December 2011



19. Total amount paid (if any) for grant of the option



NIL



20. Description of shares or debentures involved (class and number)



11,448 Ordinary 10 Pence Shares



21. Exercise price (if fixed at time of grant) or indication that price is to be
fixed at the time of exercise



10 pence per share under option



22. Total number of shares or debentures over which options held following
notification

124,988 of which:

14,161 are options under the Company Share Option Plan

82,507are Restricted Shares under the Executive Incentive Plan

28,329 are Matching Shares under the Executive Incentive Plan



23. Any additional information



Generally speaking all shares under option are subject to performance
conditions, details of which can be obtained from the office of the Company
Secretary



24. Name of contact and telephone number for queries



Justin Hoskins 01223 898589



Name and signature of duly authorised officer of issuer responsible for making
notification



Justin Hoskins, Company Secretary



Date of notification



30 December 2005

END


NOTIFICATION OF TRANSACTIONS OF DIRECTORS, PERSONS DISCHARGING MANAGERIAL
RESPONSIBILITY OR CONNECTED PERSONS

This form is intended for use by an issuer to make a RIS notification required
by DR 3.1.4R(1).


(1)   An issuer making a notification in respect of a transaction relating to
      the shares or debentures of the issuer should complete boxes 1 to 16, 23
      and 24.
(2)   An issuer making a notification in respect of a derivative relating the
      shares of the issuer should complete boxes 1 to 4, 6, 8,13, 14, 16, 23 and
      24.
(3)   An issuer making a notification in respect of options granted to a
      director/person discharging managerial responsibilities should complete
      boxes 1 to 3 and 17 to 24.
(4)   An issuer making a notification in respect of a financial instrument
      relating to the shares of the issuer (other than a debenture) should
      complete boxes 1 to 4, 6, 8, 9, 11, 13, 14, 16, 23 and 24.



Please complete all relevant boxes should in block capital letters.



1. Name of the issuer



Cambridge Antibody Technology Group plc



2. State whether the notification relates to (i) a transaction notified in
accordance with DR 3.1.4R(1)(a); or

(ii) DR 3.1.4(R)(1)(b) a disclosure made in accordance with section 324 (as
extended by section 328) of the Companies Act 1985; or

(iii) both (i) and (ii)

(ii)



3. Name of person discharging managerial responsibilities/director



Peter Chambre



4. State whether notification relates to a person connected with a person
discharging managerial responsibilities/director named in 3 and identify the
connected person



As in 3. above



5. Indicate whether the notification is in respect of a holding of the person
referred to in 3 or 4 above or in respect of a non-beneficial interest



As in 3. above



6. Description of shares (including class), debentures or derivatives or
financial instruments relating to shares



Ordinary 10 Pence Shares



7. Name of registered shareholders(s) and, if more than one, the number of
shares held by each of them



Greenwood Nominees Limited



8 State the nature of the transaction



Allotment and issue of new shares in the Company issued at the average mid
market quotation as derived from the Daily Official List for the three business
days preceding 30 December 2005 such shares having been acquired for the purpose
of the Matching Share element of the Executive Incentive Plan.



9. Number of shares, debentures or financial instruments relating to shares
acquired



2,150



10. Percentage of issued class acquired (treasury shares of that class should
not be taken into account when calculating percentage)



0.004%



11. Number of shares, debentures or financial instruments relating to shares
disposed



NIL



12. Percentage of issued class disposed (treasury shares of that class should
not be taken into account when calculating percentage)



N/A



13. Price per share or value of transaction



£6.976



14. Date and place of transaction



30 December 2005



15. Total holding following notification and total percentage holding following
notification (any treasury shares should not be taken into account when
calculating percentage)



28,592



16. Date issuer informed of transaction



30 December 2005



If a person discharging managerial responsibilities has been granted options by
the issuer complete the following boxes



17 Date of grant



30 December 2005



18. Period during which or date on which it can be exercised



30 December 2008 to 29 December 2011



19. Total amount paid (if any) for grant of the option



NIL



20. Description of shares or debentures involved (class and number)



6,450 Ordinary 10 Pence Shares



21. Exercise price (if fixed at time of grant) or indication that price is to be
fixed at the time of exercise



10 pence per share under option



22. Total number of shares or debentures over which options held following
notification

387,522 of which:

191,969 are options under the Company Share Option Plan

145,021 are Restricted Shares under the Executive Incentive Plan

50,532 are Matching Shares under the Executive Incentive Plan



23. Any additional information



Generally speaking all shares under option are subject to performance
conditions, details of which can be obtained from the office of the Company
Secretary



24. Name of contact and telephone number for queries



Justin Hoskins 01223 898589



Name and signature of duly authorised officer of issuer responsible for making
notification



Justin Hoskins, Company Secretary



Date of notification



30 December 2005

END


NOTIFICATION OF TRANSACTIONS OF DIRECTORS, PERSONS DISCHARGING MANAGERIAL
RESPONSIBILITY OR CONNECTED PERSONS

This form is intended for use by an issuer to make a RIS notification required
by DR 3.1.4R(1).


(1)   An issuer making a notification in respect of a transaction relating to
      the shares or debentures of the issuer should complete boxes 1 to 16, 23
      and 24.
(2)   An issuer making a notification in respect of a derivative relating the
      shares of the issuer should complete boxes 1 to 4, 6, 8,13, 14, 16, 23 and
      24.
(3)   An issuer making a notification in respect of options granted to a
      director/person discharging managerial responsibilities should complete
      boxes 1 to 3 and 17 to 24.
(4)   An issuer making a notification in respect of a financial instrument
      relating to the shares of the issuer (other than a debenture) should
      complete boxes 1 to 4, 6, 8, 9, 11, 13, 14, 16, 23 and 24.



Please complete all relevant boxes should in block capital letters.



1. Name of the issuer



Cambridge Antibody Technology Group plc



2. State whether the notification relates to (i) a transaction notified in
accordance with DR 3.1.4R(1)(a); or

(ii) DR 3.1.4(R)(1)(b) a disclosure made in accordance with section 324 (as
extended by section 328) of the Companies Act 1985; or

(iii) both (i) and (ii)

(ii)



3. Name of person discharging managerial responsibilities/director



Alexander Duncan



4. State whether notification relates to a person connected with a person
discharging managerial responsibilities/director named in 3 and identify the
connected person



As in 3. above



5. Indicate whether the notification is in respect of a holding of the person
referred to in 3 or 4 above or in respect of a non-beneficial interest



As in 3. above



6. Description of shares (including class), debentures or derivatives or
financial instruments relating to shares



Ordinary 10 Pence Shares



7. Name of registered shareholders(s) and, if more than one, the number of
shares held by each of them



Greenwood Nominees Limited



8 State the nature of the transaction



Allotment and issue of new shares in the Company issued at the average mid
market quotation as derived from the Daily Official List for the three business
days preceding 30 December 2005 such shares having been acquired for the purpose
of the Matching Share element of the Executive Incentive Plan.



9. Number of shares, debentures or financial instruments relating to shares
acquired



716



10. Percentage of issued class acquired (treasury shares of that class should
not be taken into account when calculating percentage)



0.001%



11. Number of shares, debentures or financial instruments relating to shares
disposed



NIL



12. Percentage of issued class disposed (treasury shares of that class should
not be taken into account when calculating percentage)



N/A



13. Price per share or value of transaction



£6.976



14. Date and place of transaction



30 December 2005



15. Total holding following notification and total percentage holding following
notification (any treasury shares should not be taken into account when
calculating percentage)



15,155



16. Date issuer informed of transaction



30 December 2005



If a person discharging managerial responsibilities has been granted options by
the issuer complete the following boxes



17 Date of grant



30 December 2005



18. Period during which or date on which it can be exercised



30 December 2008 to 29 December 2011



19. Total amount paid (if any) for grant of the option



NIL



20. Description of shares or debentures involved (class and number)



2,148 Ordinary 10 Pence Shares



21. Exercise price (if fixed at time of grant) or indication that price is to be
fixed at the time of exercise



10 pence per share under option



22. Total number of shares or debentures over which options held following
notification

66,951 of which:

31,776 are options under the Company Share Option Plan

29,640 are Restricted Shares under the Executive Incentive Plan

5,535 are Matching Shares under the Executive Incentive Plan



23. Any additional information



Generally speaking all shares under option are subject to performance
conditions, details of which can be obtained from the office of the Company
Secretary



24. Name of contact and telephone number for queries



Justin Hoskins 01223 898589



Name and signature of duly authorised officer of issuer responsible for making
notification



Justin Hoskins, Company Secretary



Date of notification



30 December 2005

END


NOTIFICATION OF TRANSACTIONS OF DIRECTORS, PERSONS DISCHARGING MANAGERIAL
RESPONSIBILITY OR CONNECTED PERSONS

This form is intended for use by an issuer to make a RIS notification required
by DR 3.1.4R(1).


(1)   An issuer making a notification in respect of a transaction relating to
      the shares or debentures of the issuer should complete boxes 1 to 16, 23
      and 24.
(2)   An issuer making a notification in respect of a derivative relating the
      shares of the issuer should complete boxes 1 to 4, 6, 8,13, 14, 16, 23 and
      24.
(3)   An issuer making a notification in respect of options granted to a
      director/person discharging managerial responsibilities should complete
      boxes 1 to 3 and 17 to 24.
(4)   An issuer making a notification in respect of a financial instrument
      relating to the shares of the issuer (other than a debenture) should
      complete boxes 1 to 4, 6, 8, 9, 11, 13, 14, 16, 23 and 24.



Please complete all relevant boxes should in block capital letters.



1. Name of the issuer



Cambridge Antibody Technology Group plc



2. State whether the notification relates to (i) a transaction notified in
accordance with DR 3.1.4R(1)(a); or

(ii) DR 3.1.4(R)(1)(b) a disclosure made in accordance with section 324 (as
extended by section 328) of the Companies Act 1985; or

(iii) both (i) and (ii)

(ii)



3. Name of person discharging managerial responsibilities/director



Lynn Lester



4. State whether notification relates to a person connected with a person
discharging managerial responsibilities/director named in 3 and identify the
connected person



As in 3. above



5. Indicate whether the notification is in respect of a holding of the person
referred to in 3 or 4 above or in respect of a non-beneficial interest



As in 3. above



6. Description of shares (including class), debentures or derivatives or
financial instruments relating to shares



Ordinary 10 Pence Shares



7. Name of registered shareholders(s) and, if more than one, the number of
shares held by each of them



Greenwood Nominees Limited



8 State the nature of the transaction



Allotment and issue of new shares in the Company issued at the average mid
market quotation as derived from the Daily Official List for the three business
days preceding 30 December 2005 such shares having been acquired for the purpose
of the Matching Share element of the Executive Incentive Plan.



9. Number of shares, debentures or financial instruments relating to shares
acquired



286



10. Percentage of issued class acquired (treasury shares of that class should
not be taken into account when calculating percentage)



0.0005%



11. Number of shares, debentures or financial instruments relating to shares
disposed



NIL



12. Percentage of issued class disposed (treasury shares of that class should
not be taken into account when calculating percentage)



N/A



13. Price per share or value of transaction



£6.976



14. Date and place of transaction



30 December 2005



15. Total holding following notification and total percentage holding following
notification (any treasury shares should not be taken into account when
calculating percentage)



2,710



16. Date issuer informed of transaction



30 December 2005



If a person discharging managerial responsibilities has been granted options by
the issuer complete the following boxes



17 Date of grant



30 December 2005



18. Period during which or date on which it can be exercised



30 December 2008 to 29 December 2011



19. Total amount paid (if any) for grant of the option



NIL



20. Description of shares or debentures involved (class and number)



Ordinary 10 Pence Shares



21. Exercise price (if fixed at time of grant) or indication that price is to be
fixed at the time of exercise



10 pence per share under option



22. Total number of shares or debentures over which options held following
notification

25,764 of which:

12,361 are options under the Company Share Option Plan

10,421 are Restricted Shares under the Executive Incentive Plan

2,982 are Matching Shares under the Executive Incentive Plan



23. Any additional information



Generally speaking all shares under option are subject to performance
conditions, details of which can be obtained from the office of the Company
Secretary



24. Name of contact and telephone number for queries



Justin Hoskins 01223 898589



Name and signature of duly authorised officer of issuer responsible for making
notification



Justin Hoskins, Company Secretary



Date of notification



30 December 2005

END


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