Synergy Healthcare Agreement

Byotrol PLC 14 November 2006 BYOTROL PLC AGREEMENT WITH SYNERGY HEALTHCARE PLC The Directors of Byotrol plc (the 'Company') are pleased to announce that the Company has entered into an agreement with Synergy Healthcare plc ('Synergy') which will see Byotrol's anti-microbial technology deployed into the NHS and independent healthcare sector in the UK and the rest of the world. Synergy Healthcare plc is a leading provider of outsourced medical services to the UK and the Netherlands, with an annualised turnover of over £130million and has over 2500 employees. Synergy has been providing sterile services in the UK since 1996 and is the UK's largest provider of decontamination and sterile services for surgical instruments. The Company operates fifteen facilities and processing approximately 40 million instruments per annum. The contract gives Synergy exclusive sales and distribution rights to Byotrol's technology in the healthcare market. In addition Synergy will market, sell and distribute Byotrol's Assure product range to the NHS and Byotrol's existing healthcare customers. In the UK, Synergy will assume responsibility for supplying products containing Byotrol to Byotrol's existing healthcare users, Sun Choice Europe Limited and DBM Holdings Ltd. The agreement will give Synergy the use of Byotrol technology in significant healthcare markets for licences, fees and options totalling £2.3 million together with an advance royalty payment of £400,000. The agreement commences immediately with the UK market and incorporates options that will grant similar rights to Synergy for both USA, Europe and the rest of the world and these are exercisable between February 2007 and February 2008. In addition to fees and royalties, Synergy will be purchasing Byotrol concentrates for use in manufacture of anti-microbial products. The agreement with Synergy demonstrates Byotrol's strategy to deploy its technology in partnership with leading businesses in its chosen markets. According to Stephen Falder, Deputy Chairman of Byotrol plc: 'This agreement will see the rapid commercialisation of Byotrol technology in the healthcare market and demonstrates our ability to licence the Company's technology to a major organisation allowing us to gain a significant and rapid penetration into one of our chosen key markets. We continue to progress discussions with several major multinationals regarding an increasing number of opportunities that have been recently identified in the Company's other target markets of Food Processing and Industrial & Technical.' - more - Dr Richard Steeves, Chief Executive of Synergy Healthcare, commented: 'The acquisition of the worldwide rights for Byotrol is a major strategic step forward for Synergy. Byotrol is an ideal fit for Synergy and, coupled with AirCleanse will greatly enhance our product offering in the atmospheric decontamination market. This is an area of critical concern to the healthcare market worldwide in order to counteract the ever-increasing threat of hospital acquired infections.' 14 November 2006 Enquiries: Byotrol plc 0161 277 9518 Stephen Falder Deputy Chairman David McRobbie Chief Executive Charles Stanley Securities 020 7149 6457 Philip Davies First City PR 0207 436 7486 Allan Piper McCann Erickson PR 01625 822540 Jim Rothnie Notes To Editors: About Byotrol Byotrol's assure range has been specifically developed for the NHS covering all areas from acute care to care homes and comprises disinfectant sprays for use across a wide range of settings, cleaning and sanitising wipes, and a hand sanitising mousse. The Company's patented technology has been proven, through extensive testing, to be effective in eradicating and controlling a wide range of organisms such as MRSA, c.difficile and e-coli. Byotrol remains active after it has dried, providing anti-microbial protection for extended periods after application and is able therefore to tackle the practical problems of odours and spoilage caused by microbe activity. Byotrol is not toxic to humans and does not require any specialist equipment or alteration to existing cleaning regimens to be effective. A further advantage of Byotrol is also its ultra low alcohol content, compared to competing products, which means it does not dry or irritate the skin when used as a hand sanitiser as part of infection control procedures. An independently supervised study carried out at Glasgow Royal Infirmary showed that daily cleaning with Byotrol's patented biocide of the ward's high contact surfaces (including door handles, tables, television handsets, patient contact systems and bed rails), representing a small fraction of the total surfaces within the ward, resulted in a significant reduction in the incidence of MRSA. The cleaning regimen, which required no special equipment or extra resource, was practised for 4 months and the incidence of MRSA was shown to have been reduced by 75% against the pre-trial condition of the ward. During this phase there were test periods with no incidence of MRSA. The Company recently obtained CE Marking status approving Byotrol for sale in medical and disinfectant products in Europe and approval from the US Environment Protection Agency for Byotrol to be used as a disinfectant, sanitiser and anti- microbial product in a broad number of market sectors. This information is provided by RNS The company news service from the London Stock Exchange

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