Purchase of Own Securities

AstraZeneca PLC
13 November 2001

                   REPURCHASE OF SHARES IN ASTRAZENECA PLC

AstraZeneca PLC announces that on 12 November 2001, it purchased for
cancellation 250,000 ordinary shares of AstraZeneca PLC at a price of 3198
pence per share. Upon the cancellation of these shares, the number of shares
in issue will be 1,750,739,034.

G H R Musker

Company Secretary

13 November 2001