Clinical Update

Allergy Therapeutics PLC
11 July 2007

11 July 2007

                            Allergy Therapeutics plc
                   ("Allergy Therapeutics" or "the Company")

                          Clinical Development Update


Allergy Therapeutics announces that clinical activity on its Pollinex Quattro
clinical studies has been placed on clinical hold by the FDA whilst the agency
fully assesses the report of a rare adverse event classified by the physician
involved as 'possibly related' to the study drug.


The Company is collaborating fully with the FDA and has provided extensive data,
both as part of the trial routine and supplementary data, including independent
expert assessment.  Allergy Therapeutics has also reviewed all the data
available to it concerning this adverse event, considers that it is unlikely
that the event was caused by the study drug and is urgently working with the FDA
to provide any additional information necessary to address and resolve FDA's
concerns.


Allergy Therapeutics has two ongoing Pollinex Quattro studies: Phase III Grass
(G301) and Phase III Ragweed (R301), and has two about to commence/recommence:
the Grass safety study (G302) and a Phase II Tree study (T204). Of these only
R301 is directly affected as it is the only trial in the treatment phase.


A full update will be provided as soon as the FDA gives material information on
the results of its review.


Keith Carter, Chief Executive of Allergy Therapeutics, said:


"The FDA has a difficult job to do in minimising risk to patients, both on
clinical trials and from marketed pharmaceuticals.  It is normal that they
should exercise caution.  We believe the evidence strongly supports the view
that the event was unlikely to have been caused by Pollinex Quattro and we are
seeking urgent clarification of the FDA's position."


There will be a conference call for analysts at 11.00am.  
Please dial [phone] to access the call.


For further information


Allergy Therapeutics                                  [phone]
Keith Carter, Chief Executive     
Tom Holdich, R&D Director

Bridgewell                                            [phone]
Shaun Dobson

Financial Dynamics                                    [phone]
Ben Brewerton


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